That's pretty much what we use, we've got one massive sub though that muggins here has to lug about. Think the desk is a soundcraft.We use two powered RCF 12" tops for anything up to a 150 person gig. We add 15"subs for anything bigger or anything outdoors.
QSC Touchmix 16 digital desk. Our sound guy subscribes to the theory that a smaller rig run hotter (6/8's of max) sounds better than a bigger rig set on 1/2....... May or may not be true - I don't know enough to argue.