Where I think it is very useful from experience, is in playing in a wedding/event band that has a huge roster of players. I was in one that had maybe 75 players who would get plugged into the schedule based on availibility. So on Friday you're working with 7 other people, and Saturday under that same band name you're playing with 7 completely different people. So they needed a unifying force to prevent all the on-the-fly edits that singers some people are prone to, and give a structure that was dependable. It was just the bass, and added keys, horns, and poorly done percussion. Stress the word "added", there were three live horns, two or three singers, and a keyboard player live.
It really is a good system they had. No rehearsals once you're past the newbie stage, and you learned new songs by 1) having the sequence emailed to you to practice with, and 2) a chopped up version of the song cut together exactly how they were going to do it. You'd get a Frankenstein-ed mp3 with chunks of three different bands playing the song, but it would match the sequence perfectly. Way ahead of its time (80s), I thought. After about twenty years the set list was unstoppable, everybody danced their heads off, the band always sounded good enough that people came up afterwards sayng how awesome we were, and in 300+ gigs I remember only one dud.
So yeah, sequences can be done right. They're also great for your time and teach you how to play to a click, which is a valuable skill.