Originally Posted by Wavelength
For a fat sound, try recording two (or more) takes of the same guitar part and pan them slightly apart. The natural inaccuracies will create an effect of space. A hint of chorus won't hurt either. Compressor should be used if you're trying to keep the volume consistent. Just go easy with it so you don't lose all the dynamics.
Good suggestions. You can even record one take with two or more different mics to get a similar result. I've recorded our guitarist with a condenser, a dynamic tom mic, and a bass drum mic, then panned and balanced the tracks to get a nice full sound.