If I was putting my hard-earned on a model I'd go for string theory, with branes colliding and creating multiple "bubble" universes. The theory has been around for a long time and after all the checking the boffins still report that the math is still "beautiful". That tends to be the case with discoveries later verified by experiment.
Trouble is we can't observe of the very big and very small. As you say, we're limited, though I suspect AI enhancements will change that situation in time.
There's millions of theism/atheism, dualist/monist arguments on the web and everyone seems sure of themselves. It's almost as if they had more of a clue than the rest of us :)
The thread needs more science videos. This one's not cool - just a lecture - but the ideas presented are something I've not heard elsewhere: https://www.youtube.com/watch?v=ElMqwgkXguw
And this video is just plain cool: https://www.youtube.com/watch?v=vT8bms2RHe8